Etiology, pathophysiology and classifications of the diabetic Charcot foot
نویسندگان
چکیده
In people with diabetes mellitus, the Charcot foot is a specific manifestation of peripheral neuropathy that may involve autonomic neuropathy with high blood flow to the foot, leading to increased bone resorption. It may also involve peripheral somatic polyneuropathy with loss of protective sensation and high risk of unrecognized acute or chronic minor trauma. In both cases, there is excess local inflammatory response to foot injury, resulting in local osteoporosis. In the Charcot foot, the acute and chronic phases have been described. The former is characterized by local erythema, edema, and marked temperature elevation, while pain is not a prominent symptom. In the latter, signs of inflammation gradually recede and deformities may develop, increasing the risk of foot ulceration. The most common anatomical classification describes five patterns, according to the localization of bone and joint pathology. This review article aims to provide a brief overview of the diabetic Charcot foot in terms of etiology, pathophysiology, and classification.
منابع مشابه
An overview of the Charcot foot pathophysiology
Charcot arthropathy of the foot is a rare but devastating complication of diabetes that remains to be a challenging issue for the foot and ankle surgeons. Charcot foot fails to be an obvious diagnostic option that comes to mind, even in a pathognomonic clinical appearance. The rarity of the disorder, more common pathologies that mimic the condition, and the self-limiting prognosis deviate the c...
متن کاملThe Usefulness of Therapeutic Diabetic Footwear and Insoles in Diabetic Foot Treatment- A Narrative Review
Orthosis and prosthesis is an expert knowledge in medical field including the design, fabrication and utilizing of orthosis and prosthesis. An orthosis is a device made of different types of material (plastic, aluminum, foam, leather, etc.) used externally on body segments to modify the structural or functional characteristics of musculoskeletal system to objectives such as: reducing pain, rest...
متن کاملCharcot Neuropathic Arthropathy of the Foot: A Literature Review and Single-Center Experience
Charcot neuropathic osteoarthropathy of the foot is a relatively common complication of diabetic neuropathy. Incorrect diagnosis and improper treatment often result in the extremity having to be amputated. This paper summarises the current view on the etiology, diagnostics, and treatment of diabetic Charcot neuropathic osteoarthropathy, with particular focus on preserving the extremity through ...
متن کاملThe role of an extended medial column arthrodesis for Charcot midfoot neuroarthropathy
The etiology of diabetic Charcot neuroarthropathy involving the midfoot often includes an inciting traumatic event or repetitive micro-trauma from an uncompensated biomechanical imbalance that potentiates an incompletely understood pathway leading to a rocker-bottom foot deformity and ulceration. In the setting of a severe Charcot foot fracture and/or dislocation with obvious osseous instabilit...
متن کاملA Review of the Pathophysiology and Clinical Sequelae of Diabetic Polyneuropathy in the Feet
Diabetic neuropathy (DN), affects approximately 50% of the people who have diabetes mellitus. It is also the ubiquitous aspect of diabetes mellitus that is a precursor to decreased quality of life and limb threatening complications from diabetes. The vast majority of patients who develop a diabetic foot ulcer (DFU) are neuropathic and all patients who develop Charcot Arthropathy are profoundly ...
متن کامل